The Fibrinolytic System

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The fibrinolytic system in pre-eclampsia.

Plasma fibrinolytic activity and plasma inhibitory activity against urokinase and tissue activator were measured in primigravidae with moderate or severe pre-eclampsia and in gestation-matched primigravidae with uncomplicated pregnancy. The mean levels of fibrinolytic activity and inhibitory activity against urokinase and tissue activator did not differ significantly between the pre-eclampsia a...

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Disorders of the blood coagulation-fibrinolytic system

Most human cells have no direct contact with the external environment and their living conditions are ensured by blood. An essential criterion for normal blood circulation is the ability of the blood to arrest bleeding at sites of tissue injury and to prevent thrombus formation inside the blood vessels under normal conditions. The balance between these two extreme states is rigorously controlle...

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Nutritional influences on the fibrinolytic system.

Fibrinolytic system In addition to the mechanisms which achieve haemostasis by the formation of fibrin-stabilized platelet plugs, man possesses an efficient system designed to remove unwanted or excessive fibrin. The enzyme which cleaves fibrin into soluble degradation products is termed plasmin (EC 3.4.4.14); it is present in the circulation as a zymogen known as plasminogen. The activation of...

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The fibrinolytic enzyme system in hypertension.

Fibrinogen, fibrinogen-related antigen (FR-antigen), and components of the fibrinolytic enzyme system were measured in patients with essential hypertension, renal disease with and without hypertension, and normal subjects. Essential hypertension was associated with a decrease in plasminogen activator and an increase in FR-antigen. In renal disease these changes were accompanied by increases in ...

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The effect of age on the fibrinolytic enzyme system.

Components of the fibrinolytic enzyme system, FR-antigen and fibrinogen, were measured in 20 healthy volunteers aged 20-40 years and in 61 elderly subjects aged 66-96 years. Plasminogen activator levels did not significantly differ between the 20-40 and 66-75 age groups, but were higher in those over 75. Plasminogen showed no change with age except for a fall in those over 75. Fibrinogen, FR-an...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1979

ISSN: 0003-4932

DOI: 10.1097/00000658-197909000-00009